Point Lisas, beyond its role as a major port, is also a significant industrial hub. Situated strategically in the Gulf of Paria, this area caters to heavy industries, particularly within the downstream energy sector. Steel mills, ammonia and methanol plants, and other industrial facilities contribute to the region's economic activity.

The Point Lisas Industrial Estate serves as the main draw, showcasing a concentration of heavy industries, power stations, and even a large water desalination plant.